Just considering it as a project ......
Related keywords. Apnea, Apnoea, CPAP, opiate toxicity, patency, apnea test, respiratory failure, cardiac arrest, Neurogenic pulmonary edema, Cardiac arrhythmias, tachycardia, Ictal tachycardia, KvLQT1, QT interval,
Copyright John Kent Andover Oct. 2009
15th May 2010.
Dog detects SUDEP symptoms without training !. (Millie, sleep Apnoea, infant)
Effect of trained Seizure Alert Dogs® on frequency of tonic-clonic seizures" Alison Palkhivala
( .... mean reduction of 43 percent (p=0.002). Nine out of the
ten patients had a 34 percent or greater reduction, four of ten had a 50 percent
or greater reduction, and only one had no improvement in seizure frequency).
"The dogs are
trained to give their owners a significant signal many minutes prior to a
seizure". "You should not have any changes to drug therapy or
medication 6 months prior to applying and throughout the assessment training
Sudden unexpected death in epilepsy (SUDEP): aclinical perspective and a search for risk factors Robert Kloster, Torstein Engelskjøn (1999)
(Sixty per cent of deaths were sleep related).
Hard Choices: Whether and How to Address SUDEP With Epileptic Patients
A study published in Seizure in 1998 found that 11 (79%) of a total of 14 patients who fell victim to SUDEP while receiving treatment at an epilepsy clinic in Wales had been taking carbamazepine.
EEG and ECG in Sudden Unexplained Death in EpilepsyNei M, Ho RT, Abou-Khalil BW, Drislane FW, Liporace J, Romeo A, Sperling MR Epilepsia 2004;45(4):338–345 [PubMed]
(Fourteen patients died in their sleep; two were awake ...)
New SCN5A mutation in a SUDEP victim with idiopathic epilepsy Seizure, Volume 18, Issue 2, Pages 158-160 D. Aurlien, T. Leren, E. Taubøll, L. Gjerstad
(DNA sequencing of the LQTS-associated genes revealed a novel missense mutation in the SCN5A gene coding for the cardiac sodium channel, voltage gated, type V, alpha subunit.
Genetic Trigger Uncovered for Sudden Death in Epilepsy. Rosemary Frei, MSc.
("We are excited, because this is the first example of a candidate gene for SUDEP" ). Baylor College of Medicine.)
Submicroscopic Rearrangements in Cardiac Arrhythmia Genes: The quest for Genetic Risk factors for SUDEP
(Alica Goldman, M.D., Ph.D)
Seizures May Indicate Underlying Cardiac Rhythm Disorder. Samson Kurt.
(ECG printout showing Torsades de pointes)
("One-third of all seizures were associated with drops in blood-oxygen levels below 90 percent. Seyal said he was surprised to find that 12 percent of these patients' blood oxygen levels actually dropped below 70 percent during their seizures").
Single gene mutation responsible for 'catastrophic epilepsy'
(" ...major motor spasms in infancy followed by cognitive dysfunction and developmental disorders such as autism").