As happens with most long-running series of books, a number of Target's Doctor Who novelisations were re-issued in omnibus form.

The first title to be released was Doctor Who and the Daleks Omnibus, a large-format book from Artus Publishing which mixed articles and picture features with abridged versions of Doctor Who and the Genesis of the Daleks and Doctor Who and the Planet of the Daleks. The book was available exlusively from the high street retailer Marks and Spencer.

1977 saw the release of the first book club edition. The Doctor Who Omnibus collected together three of Target's novelisations from the previous year, and yet again was released in hardback.

Nelson Doubleday released the first of two American omnibus editions in 1979, when The Adventures of Doctor Who collected together three Doctor Who novelisations which had previously been released in the United States as part of the ten-book range released by Pinnacle Books. A second hardback volume in 1986, unimaginatively titled The Further Adventures of Doctor Who, collected together Doctor Who and the Deadly Assassin, Doctor Who and the Face of Evil and Doctor Who and the Robots of Death, none of which had previously been available in the United States.

The final hardback omnibus to be released was the Dalek Omnibus. Released in the UK by WH Allen in 1983, the book collected together the novelisations of The Dalek Invasion of Earth, and the Third Doctor stories Day of the Daleks and Planet of the Daleks.

The twenty-fifth anniversary of Doctor Who in 1988 saw WH Allen looking to clear some space in their warehouse, and they commenced publication of a series of paperbacks which each contained two novelisations. Despite the fact that all of the titles featured a rather impressive silver foil cover, the binding made it impossible to disguise the fact that they were simply the regular paperbacks that had been stripped of the covers, chopped to size and then re-bound. The series ground to a halt after the release of the seventh title in May 1989.

Somewhat surpringly, the success of the original novels from Virgin Publishing and BBC Books between 1991 and 2005 failed to see a single omnibus version released, although with the advent of the shorter New Series Adventures to tie-in with the new television series, the chances of a modern-day omnibus hitting the shelves are probably higher than for many years.