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REFERENCES
Every effort has been
made to acknowledge the sources of research, which have
allowed me to construct this chemoinformatics project on
ATENOLOL. I would like to emphasise
that all information has been
interpreted and translated into my own words, relevant to
the course and content of the investigation.
HOME
1) "What
is a drug ?..."
Oxford English Dictionary
(page 165)
Compiled
by Ostler, G.
Clarendon Press, 1969.
2) ATENOLOL
SYNONYMS
(i) Chemical Fact Sheet
Orica Limited
January 1999
Copyright 1992–1999 Orica Limited, ACN 004 145 868.
(ii) http://chemfinder.cambridgesoft.com
(iii)http://www.rxlist.com/cgi/rxlist.cgi?drug=atenolol
2) "What
is a drug ?..."
Oxford English Dictionary
(page 165)
Compiled
by Ostler, G.
Clarendon Press, 1969.
3) "a-ten-o-lol"
pronunciation
(i) Source Wave Sound downloaded
from :
http://www.drugdigest.org/DD/DVH/Uses/0,3915,54%7CAtenolol,00.html
INTRODUCTION
1) WHAT IS ATENOLOL
?
http://www.sunderland.ac.uk/~hs0dad/profile/atenolol/what.htm
2) HYPERTENSION
(i) Keywords : "Hypertension",
"high blood pressure", "beta-blockers"
Microsoft® Encarta® Encyclopedia
2003. © 1993-2002 Microsoft Corporation. All rights reserved.
(ii) American Society Of
Hypertension ©
http://www.ash-us.org/
3) "KEY
QUESTIONS ANSWERED...BETA BLOCKER, ARRHYTHMIAS..."
THE HUTCHINSON
SCIENCE ENCYCLOPEDIA
1998 Edition
Helicon
4) "HISTORY
OF ATENOLOL"
a(i) http://www.m-web.com/iciindia/atenolol.html
b(i) Black,
Sir James Whyte
Microsoft® Encarta®
Encyclopedia 2003. © 1993-2002 Microsoft Corporation. All
rights reserved.
b(ii)
Black, Sir James Whyte - Autobiography
http://www.nobel.se/medicine/laureates/1988/black-autobio.html
5) Propranolol
(i) http://www.vitacost.com/science/hn/Drug/Propranolol.htm
6) The Top 200
Prescriptions for 2002 by Number of US Prescriptions Dispensed
(i) http://www.rxlist.com/top200.htm
PHYSICAL
1) Physical
Properties
a(i) Beilstein
Keywords : ATENOLOL, physical, enantiomers
b(i) "SO
WHICH ENANTIOMER IS ACTUALLY USED TO MAKE ATENOLOL ?"
Result from Journal found by Beilstein
J . Org. Chem. 1992, Volume 57, No. 22, 6003-6005
Lipase Catalysis in Organic Solvents. Application to the
Synthesis of (R)-
and (S)-Atenolol
H. S. Bevinakatti and A. A. Banerji
2) Physical
Properties : Solubility
(i) http://www.sunderland.ac.uk/~hs0dad/profile/atenolol/physprop.htm
3) Safety data
for ATENOLOL
(i) http://physchem.ox.ac.uk/MSDS/AT/atenolol.html
5) ATENOLOL
drug profile
(i) www.orica.com.au/resource/chemfact/
pdffiles/atenolol.pdf
SPECTROSCOPY
1) FUNDAMENTALS
OF MOLECULAR SPECTROSCOPY
Functional group, mass fragment and
general peak information
FUNDAMENTALS OF
MOLECULAR SPECTROSCOPY
Fourth edition
Colin N. Banwell and Elaine M. McCash
2) IR, MASS,
NMR SPECTRA
A special thank
you for the online e-spectra made available by
The National
Institute of Advanced Industrial Science and Technology
Tsukuba, Ibaraki, Japan
(i) http://www.aist.go.jp/RIODB/SDBS/sdbs/owa/sdbs_sea.cre_frame_disp?sdbsno=16620
SYNTHESIS
1) (i) SO WHAT IS THE MAGIC
RECIPE ? : basic understanding of mechanistic pathway
Lipase Catalysis in Organic Solvents. Application
to the Synthesis of (R)-
and (S)-Atenolol
J . Org. Chem. 1992, Volume 57, No. 22, 6003-6005
H. S. Bevinakatti and A. A. Banerji
2) What is LIPASE
?
(i) http://www.enzymeessentials.com/HTML/lipase.html
3) What is Pseudomonas
Cepacia ?
(i) http://www.agrobiologicals.com/glossary/G4464.htm
3) What is Candida
Cylindracea ?
(i) National
Library Medicine
National Center for Biotechnology
Information (NCBI)
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7788294&dopt=Abstract
BIOCHEMISTRY
1) ATENOLOL Pharmacology
(i) http://www.infomed.org/100drugs/atenphar.html
2) ATENOLOL
Biochemical pathway
(i)
http://petplace.netscape.com/articles/artShow.asp?artID=1530
3) Cardiovascular
Effects
(i)
http://synmed.snu.ac.kr/courses/graduate/medchem/wsjang.ppt
3) Nitrates,
Digoxin and Calcium Channel Blockers
(i)
http://www.usyd.edu.au/su/anaes/lectures/pforrest/Nitrates-Digoxin%20talk.htm
SIDE-EFFECTS
1) ATENOLOL TABLETS BP PRESCRIPTION
ACTUAL INFORMATION LEAFLET
ACCOMPANYING AN ATENOLOL PRESCRIPTION
(...thanks Dad !)
Patient Information Leaflet
CP Pharmaceuticals Limited
Wrexham UK
2) ATENOLOL Pharmokinetics
(i) http://www.mdbrowse.com/Druginf/a/atenolol.htm
3) ATENOLOL
Side-Effects
(i)
http://www.rxlist.com/cgi/generic/atenolol.htm
THE
FUTURE
1) (i) ATENOLOL'S OCULAR
SIDE EFFECT
a(i) Beilstein
Keywords : ATENOLOL, beta blocker,
ocular, side effect
Result from Journal found by Beilstein
ABSTRACT : Topical ophthalmic
blockers may cause release of histamine through cytotoxic
effects on inflammatory cells
Br. J. Ophthalmol., Sep 2000; 84: 1004 - 1007.
Luc M van Beek, Marcel Mulder, Nicolaas J van Haeringen,
and Aize Kijlstra
2) BETA-BLOCKER
PHARMACOLOGICAL COMPARISON
(i) http://www.toprol-xl.com/HCP/8_pharmacologya.asp
4) Immunoglobulin
E
(i)
http://www.hyperdictionary.com/dictionary/IgE
5) ATENOLOL REDUCES POSTOPERATIVE
MYOCARDIAL ISCHEMIA
National Library of Medication
Department of Anesthesia, San Francisco VA Medical Center,
University of California, USA
(i)
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=98107539
6) Effect of
Atenolol on Symptomatic Ventricular Arrhythmia Without Structural
Heart Disease: A Randomized Placebo-Controlled Study
http://www.medscape.com/content/2002/00/44/67/446751/446751_fig.html
DISCLAIMER
1) DISCLAIMER
(i)
DISCLAIMER, TERMS & CONDITIONS
http://www.ctds.info/disclaimer.html
If by any reason you are a source who have not already
been accredited or wish to submit feedback regarding the
website, please do not hestitate to contact me by e-mail
@ ravi.bhandari@imperial.ac.uk.
Alternatively, simply fill in the form below and I shall
endeavour to contact you as soon as possible.
A
SPECIAL THANK YOU...
I would to say a special
thank you to the following :
Professor
Henry Rzepa -
for
the lecture course @ C.I.T.
Mr.
Alan Ng (fellow chemist) - for enlightening me with
the wonders of the Beilstein database.
Google
Image Search - for the diversity of ATENOLOL related
results it yielded.
Animation
Factory - for the quality of animation and images provided.
FINALLY,
I THANK YOU FOR YOUR TIME AND I HOPE THIS SITE WAS AS INFORMATIVE
FOR YOU, AS IT WAS FOR ME WHILST PRODUCING IT.
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