Here arre some equations that need Solving - Questions are
Can we Goal seek ? The puzzle was built for Excel - with 24 variables.
How to maintain INTEGER SOLUTION ?
Use natural Letter column Heads for the side lengths Solution is 38 - side length of Square N in my notation.
Text of Equations.  Essentially the idea is to set the lowest few values and let the rest build up.. Assume I,J
J or X are smallest Logical order
First guess at some equations - see right for thoughts developing... G = I + J
H = G + J B = D + E + F C = O + P P = W + V H = G + J D + G + I
E = G + H A = B + D S = R + X Q = R + S E = G + H
D + G + I N = K + L R = T + X F = E + H
G = I + J M = K + N W = U + V 1) Set X, then manually solve U  B = D + E + F
F = E + H = A = B + D
2) reverse solve the top left ABMN rectangle.
A B C D E F G H I J  K L M N O  P Q R S T U V W X Y Z Now need more properties of the ABMN rectangle
unknowns L = F + E - I
55 39 81 16 9 14 4 5 3 1 18 20 56 38 30 51 64 31 33 29 35 8 43 2
Now we have sim eqn's
K = A + D + I - M Which defines it now in terms of knowns except I But is circular on M
And L is now N - K But Better L is F + E - I A+B = M + N
O = B + F + L + N - C BUT O and C defined in terms of each other. N = K + L
what about AMQ-TUC PV-T ? Ok M = K + N
T = M + N + O - Q - R Can perhaps make this into  SU - RV UX-V ?
U = R + T + V - S subs
A+B = K + 2 N
And we have 4 equations for Z  A+ B = K + 2K + 2L
Surely we just need to keep inserting all possible triplets for I,J,X until it solves.   BUT CANNOT FIND FORMULAES FOR UVK either  3K = A + B - 2 L
Seems that subtractive formulaes are like saying you have unknowns… Aha and now need to find I, J that make K integer
Try a different tack See Right scroll  2,1
So we sum of squares is Z square where Z is 5,1
AMQ QSUW WPC ABC 8,1
175 175   175 175 7,2
30625 30625 30625 30625 10,2
QSUW is directly adjustable on U to get the others closer together etc…
Have to make th Z match on bottom and Right
Started with eyeballing the Diagram in Observer 
J is smallest Now if we examine Lower corner correctly
then X, I G Assume X and U are unkown 
V looks about G + H = E S = U-X
U is huge… R=S-X
T=R-X
3025 1521 6561 256 81 196 16 25 9 1 324 400 3136 1444 900 2601 4096 961 1089 841 1225 64 1849 4 V= U+X-T
and we solved V
30625
Curiously Guess X = 2 and play with U till QSUW = WPC finds U is 35 But X=1 then U doesn't solve, 16-17
Now maybe just need to tweak I, J until AM and AB get big enough And X= 3  it is 52-53
But at sheet 5 attempt we see that with J=1 I=8 AMQ gets too big  X=4 => U= 70 and a pattern
Looks like getting near a method - for increasing X - find U then look for I,J to complete the size of top left.
Can we set up equations that Back solve the top rectangle ? - Yes - gaol seek it.
A+M = C + O = Z - Q Z=length of outer side.
A + B  = Z - C
M+N = Q + R + T - O Well yes we have it down to one unknown hence goal seek will find the others
Set A to satisfy…
z =  175 c= 81 q= 64
55 39 81 16 9 14 4 5 3 1 18 20 56 38 64 175
B=Z-C-A 1
0 M=Z-Q-A
D=A-B N=A+B-M
K=M-n
L=n-k
f=A+M-b-n-l
e=b-d-f
h=f-e Goalseek to zero 
g=e-h j=L-f-h By changing A
Hmm also h-g
i=g-j Fix some errors - look for consistency in fwd and Back
Obviously the solution is scaleable… X increasing in multiples of 2